VLDL production

VLDL_{2 largely arises from VLDL1^1,2, although some is produced in the liver, dependent on cholesterol synthesis, cholesterol ester availability and microsomal transfer protein activity.}

References
1Packard, C. J., A. Gaw, T. Demant, and J. Shepherd. 1995. Development and application of a multicompartmental model to study very low density lipoprotein subfraction metabolism.J. Lipid Res.36:172–187.

2Stalenhoef, A. F., M. J. Malloy, J. P. Kane, and R. J. Havel. 1984. Metabolism of apolipoproteins B-48 and B-100 of triglyceriderich
lipoproteins in normal and lipoprotein lipase-deficient humans. Proc. Natl. Acad. Sci. USA. 81: 1839–1843.

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